5-Amino-1MQ: The NNMT Inhibitor That Shrinks Fat and Reactivates Muscle
Quick Summary What it is: 5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) — an enzyme that becomes pathologically overactive in obese adipose tissue and senescent muscle. Mechanism: By blocking NNMT, 5-Amino-1MQ raises intracellular NAD+ and SAM levels, reactivates dormant satellite cells in muscle, and shrinks adipocytes without affecting healthy lean tissue. Who […]