Tony Huge

SAMe: The Master Methylation Molecule for Mood, Liver, and Joints

TL;DR – SAMe Methylation Protocol What: S-adenosylmethionine (SAMe) is the universal methyl donor in cellular metabolism, driving 200+ methylation reactions essential for neurotransmitter synthesis, liver detoxification, and connective tissue repair How Much: 400-800mg daily for mood and joint support; 1200-1600mg daily in divided doses for aggressive liver detoxification or depression protocols When: Morning on empty […]

D-Ribose: Refuel Your ATP Energy Engine

TL;DR – D-Ribose ATP Energy Protocol What: Five-carbon sugar that directly fuels ATP resynthesis via the pentose phosphate pathway and nucleotide salvage routes How Much: 5-10g daily for energy optimization; 15-20g daily post-intense training for accelerated ATP recovery (split into 2-3 doses) When: Post-workout within 1-2 hours for maximum ATP substrate availability; mornings for sustained […]