Tony Huge

Methylene Blue Protocol: The Mitochondrial Enhancer Tony Huge Runs

Methylene blue is the longevity compound that’s been hiding in plain sight for 150 years. It was first synthesized in 1876 as a textile dye. It became the first synthetic drug ever used in humans when Paul Ehrlich used it to treat malaria in the 1890s. It’s on the WHO essential medicines list. Veterinarians use […]

TB-500 Protocol: Tony Huge’s Real-World Healing Peptide Cycle

TB-500 sits in my fridge next to BPC-157 for a reason. They work better together than either runs alone, and after years of training in Thailand — Muay Thai, lifting, the wear and tear that comes with hitting the body hard at 50 — I’ve learned what this peptide actually does and what it doesn’t. […]

Adapalene vs Tretinoin for Men: Which Retinoid Wins for Skin in Your 40s

Men in their 40s who are serious about looksmaxxing eventually arrive at the same fork in the road: adapalene or tretinoin? Both are retinoids. Both upregulate collagen, normalize skin cell turnover, and fight wrinkles, sun damage, and acne. But they are not interchangeable, and picking the wrong one can mean six months of irritation with […]

5-Amino-1MQ: The NNMT Inhibitor That Releases Your Metabolic Brake

Quick Summary — 5-Amino-1MQ What it is: A small-molecule inhibitor of NNMT (nicotinamide N-methyltransferase) — an enzyme that throttles your body’s fat-burning capacity by depleting NAD+ precursors. Mechanism: Blocks NNMT in adipose tissue, which restores cellular methylation balance, raises NAD+ availability, and removes the metabolic governor that’s been keeping your fat cells “sleepy.” Who it’s […]