Eli Lilly Quintuple Agonist: Five Receptors, Greater Weight Loss Than Retatrutide
Eli Lilly is presenting animal data at ADA 2026 on a long-acting quintuple agonist that hits five receptors — GLP-1, GIP, glucagon, amylin, and calcitonin — and outperforms retatrutide in obese rats. Tony Huge breaks down the biochemistry, why it matters, and how it stacks with old-school rapid fat loss protocols.