Methylene Blue Explained: What the Studies Show: Tony Huge’s Video Guide
Methylene blue was a fabric dye in 1876 before it became an approved emergency medicine, and Tony Huge says he and Coach Trevor were experimenting with it as a biohacking tool a decade before anyone on YouTube mentioned it. This video is his walk through the methylene blue studies: a plain-language version of the mechanism, every dose range the trials actually used, a grade for each claim from A to E, and the one risk that has kept his own dosing low for ten years.
Cardio Doesn’t Lower Cholesterol the Way You Think: Tony Huge’s Video Guide

Cardio lowers LDL by about half a point. That is the average across 31 trials and 1,800 people, and it is the number Tony Huge builds this whole video around. Exercise is a triglyceride drug, it nudges HDL, and it barely touches the particle count that actually drives heart disease. Tony goes through the trial data, the timing trap in your blood draw, walking versus jogging, and the so-called exercise mimetics, then explains why he still thinks exercise protects the heart anyway.
My Heart Genetics Are Terrible, So I Tested Everything: Tony Huge’s Video Guide

Tony Huge calls himself a walking cardiovascular time bomb: one copy of APOE4, homozygous risk at all three standard 9p21 markers, none of the protective variants, and 14 years of testosterone and anabolics on top. Then he pulls the blood work. LDL 82.6. Lipoprotein(a) at the floor of the range. This video is his audit of both columns, what the genetics predicted, what the labs actually show, and the 30-year-old testosterone study he thinks got buried.
Methylene Blue for the Brain: What the Human Studies Show: Tony Huge’s Video Guide

A single dose of a 150-year-old textile dye raised memory retrieval scores by 7% in a randomized, placebo-controlled human trial. Tony Huge has been using methylene blue on and off for a decade, and this video is his re-check of the literature: the memory study, the poison center data, the G6PD contraindication, the MAO-A mechanism that makes it an antidepressant in disguise, and why the internet’s daily dosing walks people into the serotonin toxicity band.
Retatrutide and Heart Rate: What the Research Shows: Tony Huge’s Video Guide

Retatrutide raises heart rate. Lilly published that in its own phase 2 trial. What the scare videos and the fan videos both miss, according to Tony Huge, is the question that actually decides things: if you push that number back down with a beta blocker, are you touching the thing that raised it? He walks through the trial data, the class comparison, the outcomes pool, and the glucagon receptor mechanism, then checks his own beta blocker protocol against the research and finds a problem with it.
Ivermectin for Toxoplasma Brain Cysts? What the Research Shows: Tony Huge’s Video Guide

One in three people carries Toxoplasma gondii, the parasite that makes rodents walk toward cats and keeps turning up in studies on risk-taking and schizophrenia. Almost nobody is tested for it, and every approved drug targets the fast-moving stage while leaving the walled brain cysts alone. Tony Huge has taken ivermectin prophylactically for years after a life spent around cats. In this video he lays out the parasite’s biology, the testing that actually dates an infection, and a 2023 mouse study where a single dose of ivermectin cut brain cysts by 68.85%.
Sugar Is Aging Your Body. Can the Damage Be Reversed? Tony Huge’s Video Guide

Sugar welds itself to your proteins, and on the proteins that never turn over, that damage has been assumed permanent for 40 years. A July 2026 Nature Communications paper describes an engineered enzyme that stripped most of it off a 75-year-old human artery in a dish. Tony Huge breaks down the chemistry of glycation, what the enzyme actually did, the measurement discrepancy in the eye lens data, and then grades everything available today by whether it was measured in humans, animals, a dish, or nowhere.
Can MK-677 Make You Taller? What the Research Shows: Tony Huge’s Video Guide

Did MK-677 make Tony Huge taller? No. Wider, yes, but he started at 30 with closed growth plates. He also watched a 17-year-old grow an inch in under three months on it. This video is his attempt to reconcile those two observations with the research: the only placebo-controlled growth hormone height trial, the single seven-day MK-677 study in children, the growth plate biology that decides everything, the rat study that said no, and the cortisol counterweight nobody discussing this seems to consider.
19-Nor Steroids Explained: Nandrolone, Trenbolone, and Why They Break the Rules

A 19-nor steroid is testosterone missing the carbon-19 methyl group, and that one change explains almost everything else. The chemistry, why nandrolone picks up progesterone receptor activity testosterone never has, the prolactin mechanism behind deca dick, why 19-nor recovery drags longer than testosterone-only cycles, trenbolone’s total absence of human trials, legal status, and what WADA actually tests for.
Looksmaxxing Ranked by Evidence: What Actually Works

Softmaxxing versus hardmaxxing, graded by evidence: sleep, body fat, training and tretinoin at grade A; finasteride, fillers, limb lengthening and melanotan II broken down harms-first, with real citations and what I would never touch myself.