Topical Finasteride + Minoxidil: The 2026 Looksmaxxing Hair Protocol
TL;DR Topical finasteride + minoxidil is the looksmaxxing protocol that hits the scalp where hair loss actually happens — without the systemic libido and mood side effects of oral finasteride. Mechanism: topical 0.25% finasteride suppresses scalp DHT by 50–70% with under 5% systemic absorption; topical minoxidil 5% extends the anagen (growth) phase via potassium channel […]
5-Amino-1MQ: The NNMT Inhibitor That Unlocks NAD+ in Adipose Tissue
TL;DR 5-Amino-1MQ is a small-molecule selective inhibitor of NNMT (nicotinamide N-methyltransferase), the enzyme that drains NAD+ and SAM in aging adipose tissue and stalls fat metabolism. Mechanism: blocks NNMT, restores cellular NAD+ and methyl-donor pools in fat cells, increases adipose energy expenditure, and reverses age-related metabolic slowdown at the tissue level. Best-in-class for the lifter […]
MK-677 (Ibutamoren) Long-Term: My 2-Year Bloodwork and Honest Assessment
Two years of MK-677 use, full quarterly bloodwork, and what the GH-secretagogue actually does to glucose, IGF-1, sleep, and body composition. Plus the dosing mistakes most guys make.
PT-141 (Bremelanotide) for Men: Real Protocols for Libido and Performance
PT-141 works on the brain pathway that controls desire, not just the plumbing. Honest dosing, side effects, stacking, and who actually benefits — based on three years of personal use.
Klotho: The Anti-Aging Protein the Supplement Industry Ignores
Klotho is the longevity protein with some of the strongest data in anti-aging — but nobody is selling it. Here is what raises it and why it matters.
NAD+ Injection vs Oral NMN: What Actually Reaches Your Tissues
Oral NMN and NR sound great in marketing. Here is what the bioavailability data actually shows, and why injectable NAD+ wins on dollars and effect.
Selank Protocol: My 4-Week Self-Trial for Anxiety, Focus, and Verbal Fluency
I have run a lot of peptides through my own body. Most of them I write about after the fact. Selank is one of the few I keep coming back to, and the reason is simple: it works on something steroids, SARMs, and stimulants can’t touch — the part of your brain that decides whether […]
TB-500 (Thymosin Beta-4): The Systemic Healing Peptide That Works Where BPC-157 Can’t Reach
TB-500 isn’t a BPC-157 alternative — it’s a complement. Tony’s six-year protocol, mechanism, stacking, and bloodwork for the systemic healing peptide most users leave on the table.
Rapamycin Protocol: The mTOR Inhibitor I’ve Run for 18 Months at 5mg Weekly
Rapamycin is the only molecule with replicated lifespan extension in every mammal tested. Tony’s 18-month protocol — 5 mg weekly, food rules, bloodwork, and what most longevity influencers get wrong.
Bryan Johnson Is 10 Years Behind: SLIN Pills Solved HGH Insulin Resistance in 2016
Bryan Johnson is 10 years behind Tony Huge. The HGH-induced insulin resistance problem he’s still managing in 2026 with metformin and acarbose — Tony Huge and Coach Trevor solved it in 2016 with SLIN Pills. Independent receptor stacking, additive synergy, and bloodwork that flips the side effect into improved insulin sensitivity.