Editor note: Adapted from video.

RAD-140 vs LGD-4033: The Ultimate SARM Showdown

for Tony Huge

Runtime: 12-15 minutes

HOOK ()

What’s up guys, Tony Huge here coming at you from Thailand. Today we’re settling this once and for all – RAD-140 versus LGD-4033. I’ve run both of these compounds multiple times, I’ve experimented on myself, and I’m going to tell you exactly which one you should be using based on YOUR goals. If you want pure aggression and strength, there’s a clear winner. If you want size and fullness, different story. And if you screw up your PCT? You’re going to crash HARD. Let’s get into it.

INTRO ()

Alright, so for those of you who don’t know me, I’m Tony Huge. I’ve been self-experimenting with performance-enhancing compounds for years. I’ve injected things that would make your doctor cry. And today we’re talking about the two most popular SARMs on the market – RAD-140, also known as Testolone, and LGD-4033, Ligandrol.

Now, I want to be clear – I’m not your doctor, I’m not telling you to do any of this. What I AM doing is sharing my personal experiences and the data I’ve collected from my own body. These are research chemicals. They’re not FDA approved. But they’re also incredibly effective if you know what you’re doing.

So here’s how this is going down: First, I’m breaking down RAD-140 – mechanism of action, dosing protocols I’ve used, the results I got, and the sides. Then we do the same with LGD-4033. After that, head-to-head comparison, stacking advice, PCT requirements, and my final verdict on which one YOU should run. Let’s go.

RAD-140 (TESTOLONE) DEEP DIVE ()

Mechanism of Action

RAD-140 is a non-steroidal selective androgen receptor modulator. What does that mean in English? It binds to androgen receptors in your muscle and bone tissue, telling them to GROW, but it’s selective – meaning it’s not hitting your prostate, your hair follicles, or converting to estrogen like testosterone does. That’s the theory anyway.

In my experience, RAD-140 is the most androgenic SARM out there. It feels closer to a mild testosterone cycle than any other SARM I’ve run. You get that aggression, that drive, that “alpha” feeling. It’s real.

Dosing Protocols

Here’s what I’ve run:

• Beginner dose: 10mg per day
• Intermediate dose: 15-20mg per day (this is my sweet spot)
• Advanced/Aggressive dose: 30mg per day (I’ve gone here, and you definitely feel it, but the suppression ramps up significantly)

I dose it once per day in the morning because the half-life is 16-20 hours. You could split it, but I don’t bother.

Cycle length: 8-12 weeks. I prefer 8 weeks because the suppression gets real after that point. I’ve pushed to 12 weeks at 20mg and my total testosterone was in the low 200s by the end. We’ll talk PCT in a minute.

Results I Got

At 20mg per day for 8 weeks, here’s what happened to MY body:

• Strength gains: Massive. I added 30-40 pounds to my bench press, 50 pounds to my squat. The strength came on fast, within the first two weeks.
• Lean mass: I put on about 8-10 pounds of lean tissue. Now, some of that is glycogen and water, but the muscle density was REAL. I looked harder, more vascular.
• Fat loss: RAD-140 has a nutrient partitioning effect. I was able to recomp – build muscle while staying lean. I didn’t bulk hard, but even at maintenance calories, I was getting leaner and bigger.
• Aggression/Mental effects: This is where RAD shines. My workouts were INTENSE. I was motivated, focused, aggressive in the gym. But I also noticed I was more irritable outside the gym. My temper was shorter.

Side Effects

Let’s be real about the sides because they’re there:

• Suppression: This is the big one. RAD-140 WILL suppress your natural testosterone production. At 20mg for 8 weeks, I was at about 20-30% of my baseline testosterone. You NEED PCT. No debate.
• Liver stress: I ran bloods at week 4 and week 8. ALT and AST were elevated, about 1.5x the upper normal range. Not catastrophic, but you’re putting stress on your liver. I ran TUDCA and NAC alongside it.
• Lipids: My HDL (good cholesterol) dropped about 30%. LDL went up slightly. This is dose-dependent. The higher you go, the worse it gets.
• Hair loss: If you’re prone to male pattern baldness, RAD-140 can accelerate it. I didn’t experience this personally, but I’ve heard from guys who shed on it.
• Aggression/Mood: Like I said, I was more irritable. Some guys love this, some guys can’t handle it. If you have anger issues, be careful.
• Insomnia: I had trouble sleeping at 30mg. At 20mg, it was manageable but I definitely noticed some sleep disruption.

LGD-4033 (LIGANDROL) DEEP DIVE ()

Mechanism of Action

LGD-4033 is also a selective androgen receptor modulator, but it has a different binding affinity and profile compared to RAD-140. It’s more anabolic, less androgenic. What that means in practice is you get more size, more fullness, but less of that “alpha” aggression you get with RAD.

LGD was originally developed to treat muscle wasting, and it’s incredibly good at building tissue. If your goal is pure SIZE, LGD is your compound.

Dosing Protocols

Here’s what I’ve experimented with:

• Beginner dose: 5mg per day
• Intermediate dose: 10mg per day (this is the standard)
• Advanced dose: 15-20mg per day (I’ve gone to 20mg, and honestly, the gains beyond 10mg are marginal, but the suppression increases significantly)

I dose it once per day. Half-life is 24-36 hours, so once daily is fine.

Cycle length: 8-10 weeks. I don’t push LGD past 10 weeks because the suppression is significant, and I want to keep my gains.

Results I Got

At 10mg per day for 8 weeks:

• Lean mass: This is where LGD dominates. I put on 12-15 pounds in 8 weeks. Now, a good chunk of that is water and glycogen, but even after I came off and lost some water weight, I kept 8-10 pounds of solid muscle.
• Fullness: LGD makes you FULL. Your muscles are pumped 24/7. You look bigger, rounder, more filled out. If you’re taking Instagram pics, LGD is your friend.
• Strength gains: Good, but not as dramatic as RAD-140. I still added weight to all my lifts, but it was more gradual. Maybe 20 pounds on bench, 30-40 on squat over 8 weeks.
• Recovery: Recovery was noticeably better. I could train more frequently, handle higher volume. Muscle soreness was minimal.
• Mental effects: LGD doesn’t have the aggression of RAD. I felt good, motivated, but not that “ready to fight” feeling. It’s a cleaner experience mentally.

Side Effects

• Suppression: LGD will shut you down. At 10mg for 8 weeks, my total testosterone was around 150-200 ng/dL (normal is 300-1000+). You MUST run PCT.
• Water retention: This is the trade-off for the fullness. LGD causes noticeable water retention. I was holding 5-8 pounds of water by the end of the cycle. Some guys like the look, some guys feel bloated. I didn’t mind it.
• Liver values: ALT and AST were elevated, but less than RAD-140. Still, you’re stressing your liver. Run liver support.
• Lipids: HDL dropped about 20-25%, less impact than RAD-140, but still significant.
• Lethargy: Some guys report feeling tired on LGD, especially at higher doses or later in the cycle when suppression kicks in. I experienced mild lethargy around week 7-8.
• Hair loss: Less androgenic than RAD, so less risk, but if you’re sensitive, it can still happen.
• Libido: This is dose and time-dependent. Early in the cycle, libido is normal or even elevated. By week 6-8, as suppression increases, libido can drop. Not crashed, but noticeably lower.

HEAD-TO-HEAD COMPARISON ()

Alright, let’s break this down side by side. I’m going to give you a T-chart comparison so you can see exactly where each compound shines.

| Category | RAD-140 (Testolone) | LGD-4033 (Ligandrol) |

|—————————|——————————–|——————————–|

| Primary Goal | Strength, aggression, recomp | Size, fullness, mass building |

| Anabolic Rating | High | Higher |

| Androgenic Feel | Very androgenic, “alpha” | Less androgenic, cleaner |

| Lean Mass Gains | 8-10 lbs (8 weeks at 20mg) | 12-15 lbs (8 weeks at 10mg) |

| Strength Gains | Massive, rapid | Good, gradual |

| Water Retention | Minimal | Moderate to high |

| Muscle Fullness | Hard, dry, vascular | Full, round, pumped |

| Fat Loss/Recomp | Excellent | Moderate |

| Aggression/Drive | High, can be irritable | Moderate, stable |

| Suppression (8 weeks) | Severe (70-80% shutdown) | Severe (70-80% shutdown) |

| Liver Stress | Moderate (ALT/AST 1.5x+) | Mild-Moderate (ALT/AST 1.2-1.5x) |

| Lipid Impact | HDL down 30%, LDL up | HDL down 20-25%, LDL up |

| Hair Loss Risk | Higher (if prone) | Lower (but still possible) |

| Sleep Impact | Can disrupt sleep | Minimal impact |

| Libido | Maintained longer | Drops sooner (week 6+) |

| Best For | Powerlifters, fighters, recomp | Bodybuilders, bulkers, mass |

| Dosing Sweet Spot | 15-20mg per day | 10mg per day |

| Cycle Length | 8 weeks (max 12) | 8-10 weeks |

My Take on the Comparison

Here’s the reality: Both compounds are going to suppress you. Both are going to stress your liver. Both are going to mess with your lipids. The question is, what are you trying to achieve?

RAD-140 is for the guy who wants to feel like a savage in the gym. You want PRs every week. You want to be aggressive, focused, intense. You want to recomp – build muscle while staying lean. You’re okay with being a little irritable. You’re a powerlifter, a fighter, or you just want that edge.

LGD-4033 is for the guy who wants SIZE. You want to look full, jacked, pumped. You’re okay with holding a little water if it means you look bigger in the mirror. You’re a bodybuilder, or you’re just trying to bulk up. You want steady, consistent gains without the mental intensity of RAD.

Personally? I prefer RAD-140 when I’m cutting or recomping. I prefer LGD-4033 when I’m bulking. But that’s just me.

WHO SHOULD USE WHICH + STACKING ADVICE ()

Who Should Use RAD-140?

• You’re experienced with SARMs or steroids (this is NOT a beginner compound)
• Your primary goal is strength and power
• You want to recomp – build muscle while losing fat
• You thrive on aggression and intensity in the gym
• You’re okay with harsher sides for better results
• You’re a competitive athlete (powerlifter, fighter, etc.)

Stacking RAD-140:

I’ve stacked RAD-140 with:

• Cardarine (GW-501516): 10-20mg per day. This helps with endurance and lipids. Great for cutting or recomp.
• MK-677: 12.5-25mg per day. Helps with recovery, sleep, and appetite. Takes the edge off RAD’s intensity.
• Testosterone base: If you’re going to run RAD at high doses (25mg+), I recommend a low-dose testosterone base (100-150mg/week) to avoid full shutdown. This is advanced, but it’s what I do.

DO NOT stack RAD-140 with other highly suppressive compounds unless you’re running a test base. Stacking RAD with LGD or another strong SARM without a test base is asking for a shutdown and feeling like garbage.

Who Should Use LGD-4033?

• You’re newer to SARMs (LGD is more forgiving mentally)
• Your primary goal is building mass
• You want to bulk up and don’t mind holding water
• You prefer stable mood and energy
• You’re a bodybuilder or physique competitor
• You want a “cleaner” experience

Stacking LGD-4033:

I’ve stacked LGD-4033 with:

• MK-677: 12.5-25mg per day. This is a MASS monster combo. You’ll blow up. Appetite goes through the roof, recovery is insane, and the fullness is unreal. Expect to gain 15-20 pounds in 8 weeks, but a lot of it is water.
• Cardarine (GW-501516): 10-20mg per day. Helps offset the lipid damage and improves conditioning while bulking.
• S4 (Andarine): 50mg per day. Adds hardness and vascularity to the fullness from LGD. Good for a lean bulk.

Again, don’t stack multiple suppressive SARMs without a test base unless you want to feel terrible.

PCT REQUIREMENTS ()

Let’s be crystal clear: You NEED post-cycle therapy for both RAD-140 and LGD-4033. Anyone who tells you otherwise is lying or hasn’t run blood work.

My PCT Protocol (Same for Both)

I start PCT the day after my last dose. Here’s what I run:

Weeks 1-4:

• Nolvadex (Tamoxifen): 20mg per day (some guys do 40mg for week 1, then 20mg for weeks 2-4, but I find 20mg is sufficient)
• Optional: Clomid (Clomiphene): 25mg per day (I only add this if I ran a longer cycle or higher doses)

Supporting supplements throughout PCT:

• Vitamin D3: 5,000 IU per day
• Zinc: 30mg per day
• Ashwagandha: 600mg per day (helps with cortisol and recovery)
• DHEA: 50mg per day (helps kickstart hormonal recovery)

Blood work:

• Get blood work 4 weeks AFTER finishing PCT to confirm your testosterone has recovered
• If you’re still suppressed, extend PCT or see a doctor

What Happens if You Don’t Run PCT?

You’re going to feel like absolute garbage. Low energy, no libido, depression, loss of muscle, fat gain. Your body needs help recovering its natural testosterone production. Don’t skip this.

Suppression Levels

From my experience and blood work:

• RAD-140 at 20mg for 8 weeks: Total testosterone drops to 150-250 ng/dL (70-80% suppression)
• LGD-4033 at 10mg for 8 weeks: Total testosterone drops to 150-200 ng/dL (70-80% suppression)

Both compounds suppress you HARD. There’s no way around it.

VERDICT ()

Alright, final verdict time.

If I had to choose ONE compound to run for the rest of my life, it would be RAD-140. Why? Because I value strength, aggression, and the ability to recomp. I like feeling like a savage. I like the mental edge. And I respond really well to it.

But here’s the thing – your goals might be different. If you’re trying to bulk up and you want to put on as much size as possible, LGD-4033 is objectively better for that purpose. You’ll gain more total mass, you’ll look fuller, and it’s easier on your mental state.

My recommendation:

• First-time SARM user? Start with LGD-4033 at 5-10mg for 8 weeks. It’s more forgiving, less intense, and you’ll still make great gains.
• Experienced user who wants strength and aggression? RAD-140 at 15-20mg for 8 weeks.
• Experienced user who wants mass? LGD-4033 at 10mg for 8-10 weeks.

Both compounds require:

• Liver support (TUDCA, NAC)
• Lipid support (Cardarine, fish oil, or statins if needed)
• Blood work before, during, and after
• Proper PCT (Nolvadex minimum)

And look, I’m going to say this one more time: these are research chemicals. They work. They work really well. But they come with risks. You’re suppressing your natural hormones. You’re stressing your liver. You’re impacting your lipids. If you’re not willing to run blood work and do this responsibly, don’t do it at all.

That’s it, guys. RAD-140 vs LGD-4033. If you found this useful, smash that like button, drop a comment letting me know which one you’d run, and subscribe for more unfiltered, real-world data on performance-enhancing compounds.

I’m Tony Huge, and I’ll see you in the next one.

[END]

VIDEO NOTES / METADATA

Title Ideas:

• RAD-140 vs LGD-4033: The REAL Difference (Blood Work Included)
• Testolone vs Ligandrol: Which SARM Is BETTER?
• I Ran RAD-140 AND LGD-4033 – Here’s What Happened

Thumbnail:

• Split image: left side RAD-140 with “STRENGTH” overlay, right side LGD-4033 with “SIZE” overlay
• Tony Huge flexing in center

Tags:

RAD-140, LGD-4033, SARMs, Testolone, Ligandrol, Tony Huge, performance enhancing drugs, bodybuilding, muscle building, PCT, testosterone suppression, SARM comparison, biohacking

Description:

In this video, I break down the two most popular SARMs on the market – RAD-140 (Testolone) and LGD-4033 (Ligandrol). I’ve run both compounds multiple times and I’m sharing my real-world results, side effects, dosing protocols, and blood work data. Whether you’re looking for strength, size, or a recomp, I’ll tell you exactly which SARM you should run.

⚠️ DISCLAIMER: This content is for educational and entertainment purposes only. SARMs are research chemicals not approved for human consumption. Always consult a medical professional before using any performance-enhancing compounds.

Timestamps:

0:00 – Hook

0:30 – Intro

1:30 – RAD-140 Deep Dive

4:30 – LGD-4033 Deep Dive

7:30 – Head-to-Head Comparison

10:30 – Stacking & Who Should Use Which

12:30 – PCT Requirements

13:30 – Final Verdict

END OF SCRIPT