Hexarelin Review: Mechanism, Dosage, and Cardiac Risk
Hexarelin is the strongest acute GH pulse of any studied GHRP, and the one with the highest cortisol, ACTH, and prolactin cost. The mechanism, what the human trials dosed, why it desensitizes with daily use, the real cardiac research, and how it stacks up against ipamorelin and CJC-1295.
Enclomiphene vs Clomid: Same Molecule, Opposite Effects
Clomid is 62% enclomiphene and 38% zuclomiphene. Enclomiphene clears in hours; zuclomiphene lingers near 30 days and carries the estrogenic side effects. Here is what 5 trials, the FDA’s 2015 rejection of Androxal, and enclomiphene’s compounded-only status in 2026 mean for which one to run.
HCG With TRT: Keep Your Testicles, Fertility and Estrogen
HCG substitutes for the LH signal that TRT shuts off, keeping the testes making testosterone and sperm locally. Covers the 2020 compounding ban and current prescription status, the estradiol tradeoff, the 125-500 IU EOD dosing trials, and what bloodwork to run before assuming it is working.
NMN vs NR: Which NAD+ Precursor Raises NAD+ More
NMN and NR both raise blood NAD+ in human trials, but they enter the chain at different points and the real bottleneck, CD38, sits downstream of both. Here’s what the trials show, my Law 2 breakdown, and the Natural Plus Protocol take.
Heavy Lifting, Bone Density and Longevity: Tony Huge’s Video Guide
Heavy lifting can help preserve strength and improve bone density as you age. The harder question is whether moving an enormous weight a few inches does more for longevity than a well-designed strength program. In this video, Tony Huge explores that idea through training with Sensei Don, grip-strength research, and the case for loading your […]
Protection Starts on Day One
A coach flew across the world this week to ask me questions for 50 minutes. He tried to make the trip last year and couldn’t. We had met once before at an expo, a few minutes in a crowd, and it wasn’t enough, so this year he got on a plane just for the conversation. […]
Connor Murphy Death: Looksmaxxing Risks & Mental Health
The bodybuilding and fitness community was shaken by the tragic news of Connor Murphy’s death at age 32, with reports from the New York Post revealing disturbing details about the final chapter of the influencer’s life. Murphy, who gained millions of followers through his physique transformation videos and later became associated with the “looksmaxxing” movement, […]
The FDA Peptide Crackdown: Regulatory Capture, Not Patient Safety
BPC-157, GHK-Cu, MOTS-c, and a dozen other peptides have been pushed off the legal compounding market. The justification is safety. The reality is regulatory capture. Here is the honest read.
Purpose vs Biohacking: What Really Drives Healthy Aging?
The biohacking and longevity optimization community has been hit with a provocative claim: having a sense of purpose may be more crucial to healthy aging than the arsenal of peptides, supplements, and interventions that enthusiasts like Tony Huge have long advocated. According to a recent report from Daily Maverick, research is increasingly pointing toward psychological […]
Looksmaxxing Debate: Tony Huge’s Biohacking Perspective
The intersection of physical optimization, social media trends, and political discourse has created a new flashpoint in the world of self-improvement. When Representative Alexandria Ocasio-Cortez recently voiced concerns about young men pursuing “looksmaxxing” strategies, social media influencer Clavicular responded, sparking a broader conversation about appearance optimization that directly relates to the biohacking and bodybuilding communities […]