Peptide Dosage Calculator: Body Weight Protocol

Most People Are Dosing Peptides Wrong — Here’s the Math

You bought the peptide. You reconstituted it (hopefully following my reconstitution guide). Now you’re staring at an insulin syringe trying to figure out how many units equals the dose you need. And you’re guessing.

Stop guessing. Tony Huge’s Law #5 of Biochemistry Physics: precision determines results. The difference between an effective peptide dose and a wasted one often comes down to a few micrograms. This guide gives you the exact math — once, permanently.

Understanding Peptide Measurement Units

Micrograms (mcg) vs Milligrams (mg)

1 mg = 1,000 mcg. Most peptide doses are measured in micrograms. When someone says “250mcg of BPC-157,” that’s 0.25mg. Always double-check which unit the protocol uses — a 10x dosing error because you confused mg and mcg is not uncommon.

International Units (IU)

Growth hormone peptides (HGH, MK-677 oral) and insulin are measured in IU. There is NO universal conversion between IU and mcg — it depends on the specific compound’s biological activity. For HGH: 1 IU ≈ 0.33mg.

Syringe Units

A standard U-100 insulin syringe holds 100 units = 1mL. Each “tick” on a typical 0.5mL syringe = 1 unit = 0.01mL. The dose in syringe units depends entirely on your reconstitution concentration.

The Universal Reconstitution Formula

This is the formula that applies to every peptide, every time:

Dose in syringe units = (Desired dose in mcg × Total water added in mL × 100) ÷ Total peptide in vial in mcg

Or simplified: Units to draw = (Desired mcg ÷ mcg per unit)

Where: mcg per unit = Total mcg in vial ÷ (Total mL of water × 100)

Practical Example: BPC-157

Vial: 5mg (5,000mcg) of BPC-157. You add 2mL of bacteriostatic water.

• Concentration: 5,000mcg ÷ 200 units = 25mcg per unit
• For a 250mcg dose: 250 ÷ 25 = 10 units on the syringe
• For a 500mcg dose: 500 ÷ 25 = 20 units on the syringe

Practical Example: CJC-1295 + Ipamorelin

Vial: 2mg (2,000mcg) CJC-1295. Add 1mL BAC water. (Full CJC-1295 + Ipamorelin guide here)

• Concentration: 2,000mcg ÷ 100 units = 20mcg per unit
• For 100mcg dose: 100 ÷ 20 = 5 units
• For 300mcg dose: 300 ÷ 20 = 15 units

Body Weight Dosing Guidelines

Many peptides scale with body weight. Here’s the framework used in the Enhanced Athlete Protocol — Peptides section:

Growth Hormone Secretagogues

• CJC-1295/Ipamorelin: 1-2mcg/kg per injection. 80kg person = 80-160mcg each, 2-3x daily
• Hexarelin: 1-2mcg/kg. 80kg = 80-160mcg, 2-3x daily (desensitization at 4-6 weeks)
• GHRP-2/GHRP-6: 1-2mcg/kg, 2-3x daily on empty stomach
• Sermorelin: 2-3mcg/kg, typically 200-300mcg before bed

Healing Peptides

• BPC-157: 3-5mcg/kg, 2x daily. 80kg = 250-400mcg per dose
• TB-500: Loading: 25-50mcg/kg/week (split into 2 doses). Maintenance: 10-25mcg/kg/week
• GHK-Cu: 1-3mcg/kg daily. 80kg = 100-200mcg subcutaneous

Cognitive Peptides

• Semax: 200-600mcg intranasal (not weight dependent — nasal absorption is fixed)
• Selank: 200-400mcg intranasal
• Dihexa: 1-5mg oral or intranasal (NOT weight-scaled — start low)

Anti-Aging Peptides

• Epitalon: 5-10mg daily for 10-20 day cycles, 2-3x per year
• FOXO4-DRI: 3-5mg/kg for 3 consecutive days, monthly or quarterly
• Thymosin Alpha-1: 1.6mg subcutaneous, 2x weekly (fixed dose, not weight-scaled)

Quick Reference Reconstitution Chart

Standard reconstitution ratios (using bacteriostatic water):

• 5mg vial + 1mL water = 50mcg per unit (good for higher-dose peptides like BPC-157, TB-500)
• 5mg vial + 2mL water = 25mcg per unit (easier precision for moderate doses)
• 2mg vial + 1mL water = 20mcg per unit (common for GH secretagogues)
• 10mg vial + 2mL water = 50mcg per unit (for larger vials)

Always store reconstituted peptides in the refrigerator and follow the peptide storage guide for maximum potency preservation.

Common Dosing Mistakes

• Confusing mg and mcg — a 1mg dose when you meant 100mcg is a 10x overdose
• Not accounting for reconstitution volume — adding different amounts of water changes your concentration
• Using the wrong syringe — U-100 and U-40 syringes have different scales
• Ignoring timing — GH secretagogues must be taken on an empty stomach; food blunts the GH pulse
• No cycling — review the peptide cycling guide to avoid receptor desensitization

Interesting Perspectives

While the core math of peptide dosing is non-negotiable, the application of these principles reveals deeper layers of the Tony Huge Laws of Biochemistry Physics. Precision dosing isn’t just about avoiding error; it’s about exploiting non-linear biological responses. For instance, the difference between a 1mcg/kg and 2mcg/kg dose of a GHRP isn’t just “double the effect”—it can mean the difference between a physiological pulse and a supraphysiological surge that maximizes mTOR activation for growth. This dose-response non-linearity is a cornerstone of the framework. Furthermore, the concept of body-weight scaling is being challenged in advanced circles for certain peptides with central nervous system activity, like Dihexa, where blood-brain barrier permeability may be the limiting factor, not total body mass. The most precise calculators in the world are useless without understanding the why behind the number—knowing when to adhere strictly to mcg/kg and when to treat the guideline as a starting point for individual titration based on receptor feedback and downstream biomarkers.

Precision Is the Enhanced Man’s Edge

Anyone can buy peptides. The Enhanced Man knows exactly how to dose them. This calculator framework applies to every peptide in the EA Protocol peptide system. Master the math once, and you’ll never guess at a dose again.