Hair Preservation on Natty Plus: Keeping Your Gains and Your Hair

Already Enhanced. Now Optimize Your Hair.

The Natty Plus Protocol delivers muscle gains that rival steroids without shutting down your natural hormone production. But there’s one side effect nobody talks about until it’s too late — your hairline. I’ve watched Connor Murphy transform from a 157-pound skeleton to 220 pounds of muscle while actually improving his hair quality. That’s not accident. That’s protocol.

Most guys think they have to choose: keep their hair or build their physique. That’s old-school thinking. On Natty Plus, you can have both — but only if you understand which compounds threaten your follicles and which ones protect them.

The DHT Reality Check

Let’s cut through the hair loss confusion. Androgenic alopecia — male pattern baldness — happens when dihydrotestosterone (DHT) binds to receptors in your hair follicles. DHT is five times more androgenic than testosterone, and it progressively miniaturizes your follicles until they stop producing hair entirely.

Here’s what most people miss: DHT isn’t the villain. It’s essential for masculine development, sex drive, and muscle hardness. The problem is sensitivity. Some guys can blast grams of testosterone with zero hair loss. Others lose hair from looking at a bottle of creatine too hard.

The key is knowing your genetic predisposition and managing DHT locally — at the scalp — without systemically crushing this crucial hormone. That’s where strategic hair preservation comes in. This is a direct application of the Tony Huge Laws of Biochemistry Physics: you must manage receptor sensitivity and local hormone conversion without destroying systemic function.

Reading Your Genetics

Before starting any enhancement protocol, assess your hair loss risk. Look at your maternal grandfather’s hairline at your current age. Check for miniaturization around your temples and crown. If you’re already thinning, you’re DHT-sensitive and need aggressive prevention from day one.

Connor Murphy had the advantage of starting with good hair genetics, but even he implements prevention protocols because some Natty Plus compounds can accelerate androgenic alopecia in predisposed individuals.

Hair-Safe Natty Plus Compounds

Not all Natty Plus compounds threaten your hairline. Here’s the breakdown of what you can use without worry:

MK-677 (Growth Hormone Secretagogue)

This is your hair’s best friend. MK-677 increases growth hormone and IGF-1, both of which support hair follicle health and growth. Connor experienced a 15x increase in growth hormone levels on his protocol, and this likely contributed to his improved hair quality.

I take 25mg daily, usually before bed. The increased growth hormone supports hair follicle regeneration while you sleep. Zero androgenic activity means zero hair loss risk.

Enclomiphene

This selective estrogen receptor modulator blocks estrogen at the pituitary while allowing it to work peripherally. The result? Increased natural testosterone production without the DHT conversion issues you get with exogenous testosterone.

Connor doubled his testosterone from 340 to 700 ng/dL in 11 days using enclomiphene. Because it’s boosting your natural production rather than replacing it, you avoid the DHT spikes that come with testosterone injections.

Creatine

Despite internet hysteria about creatine causing hair loss, the evidence is weak. One study showed a modest increase in DHT, but no studies directly link creatine to accelerated hair loss. I’ve used 5 grams daily for years with zero impact on my hairline.

If you’re extremely DHT-sensitive, monitor your response during the first month. Most guys see zero issues.

Hair-Threatening Compounds

These Natty Plus compounds require careful consideration and aggressive prevention protocols:

SARMs (Selective Androgen Receptor Modulators)

Despite the “selective” marketing, most SARMs can accelerate hair loss in predisposed individuals. RAD-140, S23, and YK-11 are particularly harsh on hairlines. LGD-4033 and Ostarine are milder but still carry risk.

If you’re using SARMs, implement the full hair preservation stack immediately. Don’t wait to see if you’re affected — prevention is easier than restoration.

Prohormones

1-Andro, 4-Andro, and other prohormones convert to testosterone and DHT in the body. They’re essentially steroid precursors, which means they carry similar hair loss risks to actual steroids.

The conversion rate varies by individual, but if you’re prone to hair loss, prohormones will accelerate it. Use the complete prevention protocol or avoid these compounds entirely.

Connor Murphy’s Hair Regrowth Protocol

Connor didn’t just maintain his hair on Natty Plus — he actually improved it. Here’s his exact approach:

The Foundation: Finasteride

Finasteride blocks 5-alpha-reductase, the enzyme that converts testosterone to DHT. Connor uses 1mg daily, which reduces scalp DHT by approximately 70% while only reducing serum DHT by 30%.

This selective reduction preserves most of DHT’s benefits while protecting the hair follicles. Some guys worry about side effects, but at 1mg daily, the incidence is under 2%.

Topical Minoxidil

Connor applies 5% minoxidil foam twice daily to his hairline and crown. Minoxidil works by increasing blood flow to follicles and extending the anagen (growth) phase of the hair cycle.

The key is consistency. Minoxidil takes 4-6 months to show results, and stopping it causes rapid shedding of any hair it was supporting. Once you start, you’re committed.

Ketoconazole Shampoo

Connor uses 2% ketoconazole shampoo three times per week. Ketoconazole is antifungal, but it also has mild anti-androgenic properties at the scalp level. It reduces local DHT production and inflammation.

Use it as your regular shampoo on designated days, leaving it on for 3-5 minutes before rinsing. It’s harsh, so follow with a good conditioner.

The Current Topical Hair Potion Recipe

This is the cutting-edge topical formula we’re currently experimenting with. It combines multiple mechanisms for maximum hair preservation and regrowth:

Base Formula (per 60ml bottle):

• Minoxidil: 5% (3000mg) — vasodilator and growth stimulator
• Finasteride: 0.1% (60mg) — topical DHT blocker
• Tretinoin: 0.025% (15mg) — enhances absorption and stimulates follicles
• Ketoconazole: 2% (1200mg) — anti-androgenic and antifungal
• Caffeine: 1% (600mg) — stimulates follicles and blocks DHT locally
• Azelaic Acid: 5% (3000mg) — 5-AR inhibitor and anti-inflammatory

Vehicle:

• Propylene Glycol: 40% — solvent and penetration enhancer
• Ethyl Alcohol: 30% — solvent and antimicrobial
• Purified Water: Make up to 100%

Apply 1ml to affected areas twice daily. The combination of systemic DHT reduction (finasteride) with topical growth stimulation (minoxidil) and local anti-androgenic activity creates a comprehensive approach.

Advanced Additions

For guys with aggressive hair loss, we’re experimenting with these additions:

• RU58841: 50mg daily — topical anti-androgen with zero systemic absorption
• Copper Peptides: 2mg — stimulate hair follicle growth factors
• Adenosine: 0.75% — extends anagen phase and thickens hair

These require compounding pharmacy preparation. Standard formulations don’t include these advanced ingredients.

Timing Your Hair Protocol

Prevention beats restoration every time. If you’re planning to run SARMs or prohormones, start your hair protocol 2-4 weeks before beginning the cycle. This gives the protective compounds time to build up in your system.

Pre-Cycle Phase (4 weeks before):

• Start finasteride 1mg daily
• Begin minoxidil twice daily
• Switch to ketoconazole shampoo
• Get baseline hair photos

On-Cycle:

• Continue all prevention protocols
• Add topical potion if using harsh compounds
• Monitor for increased shedding
• Take progress photos monthly

Post-Cycle:

• Continue finasteride and minoxidil indefinitely
• Assess results at 6-month mark
• Adjust protocol based on response

Monitoring and Adjustments

Your hair responds slowly to both damage and treatment. Monthly photos under consistent lighting are more valuable than daily mirror checks. Focus on these areas:

• Hairline recession: Measure temple points
• Crown thinning: Photo from above in bright light
• Overall density: Part your hair in multiple locations
• Hair quality: Thickness and texture changes

If you notice acceleration despite prevention protocols, you have three options: add more aggressive treatments, reduce androgenic compounds, or accept the trade-off.

The Bloodwork Connection

Regular bloodwork helps optimize your hair protocol. Key markers to track:

Hormonal Panel:

• Total Testosterone: Should remain stable on finasteride
• DHT: Expect 30% reduction on finasteride
• Estradiol: Monitor for increases from DHT suppression
• SHBG: Affects free hormone levels

Nutritional Support:

• Iron: Deficiency causes diffuse thinning
• Zinc: Essential for hair growth
• Biotin: Hair quality and strength
• Vitamin D: Follicle cycling

Connor’s bloodwork throughout his Natty Plus journey showed stable hormones with improved testosterone production, proving you can enhance performance while protecting hair.

Interesting Perspectives

The conversation around hair preservation in the enhancement community is evolving. While the standard finasteride/minoxidil protocol is foundational, there are emerging angles and unconventional applications worth considering. Some biohackers are exploring the use of low-level laser therapy (LLLT) caps in conjunction with topical anti-androgens, theorizing that the increased blood flow and cellular energy may enhance the efficacy of compounds like RU58841. Others are looking at the role of scalp microbiome health, using prebiotic topicals to reduce inflammation that can exacerbate follicle miniaturization. A contrarian take gaining traction is the strategic, pulsed use of more aggressive topical anti-androgens only during cycles of highly androgenic SARMs like RAD-140, rather than continuous use, to minimize potential long-term receptor adaptation—a concept that aligns with the Tony Huge Laws of Biochemistry Physics regarding receptor saturation and cycling. Furthermore, the cross-domain application of peptides like GHK-Cu and BPC-157 for wound healing is being experimentally translated to scalp treatments, with anecdotal reports suggesting they may help repair miniaturized follicles when delivered via microneedling.

Realistic Expectations

Hair restoration is slow. Finasteride takes 6-12 months to show full effects. Minoxidil requires 4-6 months minimum. The topical potion combinations are experimental — we’re tracking results but don’t have long-term data yet.

What you can expect:

Month 1-3:

• Possible increased shedding (normal response)
• Scalp adjustment to new products
• No visible improvements yet

Month 3-6:

• Shedding normalizes
• First signs of regrowth
• Existing hair may thicken

Month 6-12:

• Significant improvement in responsive individuals
• Stabilization of hair loss
• Need to assess and adjust protocol

The Financial Reality

Quality hair preservation isn’t cheap, but it’s less expensive than hair transplants. Monthly costs:

• Generic Finasteride: $10-20
• Minoxidil foam: $25-40
• Ketoconazole shampoo: $15-25
• Topical potion (compounded): $80-150
• Advanced ingredients: $100-200

Total monthly investment: $230-435 for the complete protocol. Compare that to $15,000-25,000 for a hair transplant that doesn’t address the underlying problem.

Citations & References

Taking Action

The Natty Plus Protocol can transform your physique without destroying your hairline — if you’re proactive. Connor Murphy proves it’s possible to gain 65 pounds of muscle while actually improving hair quality.

Start with the basics: finasteride, minoxidil, and ketoconazole shampoo. Add the advanced topical potion if you’re using harsh compounds. Monitor with photos and bloodwork. Adjust based on results.

Remember — hair loss prevention is infinitely easier than restoration. Don’t wait until your hairline is retreating to start caring about it. Already enhanced, now optimize everything, including what’s on top of your head.

The choice is yours: keep making excuses about genetics, or start the protocol that lets you build your dream physique while keeping your hair. Connor Murphy chose optimization. What will you choose?